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ktrC [2017-07-03 14:35:51]
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ktrC [2017-07-03 14:35:51]

low affinity potassium transporter KtrC-KtrD, peripheric membrane component
Locus
BSU14510
Isoelectric point
5.63
Molecular weight
24.20 kDa
Protein length
221 aa Sequence Blast
Gene length
663 bp Sequence Blast
Function
potassium uptake
Product
low affinity potassium transporter KtrC-KtrD, peripheric membrane component (proton symport)
Essential
no
Synonyms
ylxV,yzaC,ykqB

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
1,520,531 → 1,521,196

The protein

Paralogous protein(s)

Domains

  • contains a RCK_N domain at the N-terminus (according to UniProt)
  • contains a c-di-AMP-binding RCK_C domain at the C-terminus (according to UniProt) PubMed
  • Effectors of protein activity

  • the protein binds c-di-AMP PubMed
  • Structure

  • 4J7C (the KtrA-KtrB complex, 56% identity) PubMed
  • 4XTT (the S. aureus KtrA RCK_C domain in complex with c-di-AMP, 57% identity) PubMed
  • Localization

  • peripheral membrane protein PubMed
  • Expression and Regulation

    Operons

    Genes
    Description

    Regulation

  • constitutively expressed PubMed
  • view in new tab

    Description

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
  • Regulatory mechanism

  • Spo0A: activation, PubMed, in Spo0A regulon
  • Regulation

  • constitutively expressed PubMed
  • view in new tab

    Biological materials

    Mutant

  • MGNA-A904 (ykqB::erm), available at the NBRP B. subtilis, Japan
  • GHB6 (ktrC::spec), PubMed (available in Erhard Bremer's and Jörg Stülke's) labs, available at BGSC as 1A955
  • GP2264 (ktrC::aphA3), available in Jörg Stülke's lab PubMed
  • GP2048 (ktrC::cat), available in Jörg Stülke's lab PubMed
  • GP2079 (ktrC::tet), available in Jörg Stülke's lab PubMed
  • GP2083 (D(ktrA-ktrB)::aphA3 DktrC::tet), available in Jörg Stülke's lab
  • Expression vector

  • pGP2907 (N-terminal His-tag, purification from E. coli, in pWH844), available in Jörg Stülke's lab
  • Labs working on this gene/protein

  • Erhard Bremer, University of Marburg, Germany homepage
  • References

    Reviews

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    Original publications

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